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Chloride channel accessory 1 integrates chloride channel activity and mTORC1 in aging‐related kidney injury

The mechanism of kidney injury in aging are not well understood. In order to identify hitherto unknown pathways of aging‐related kidney injury, we performed RNA‐Seq on kidney extracts of young and aged mice. Expression of chloride (Cl) channel accessory 1 (CLCA1) mRNA and protein was increased in th...

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Detalles Bibliográficos
Autores principales: Lee, Hak Joo, Donati, Andrew, Feliers, Denis, Sun, Yuyang, Ding, Yanli, Madesh, Muniswamy, Salmon, Adam B., Ikeno, Yuji, Ross, Corinna, O'Connor, Christopher L., Ju, Wenjun, Bitzer, Markus, Chen, Yidong, Choudhury, Goutam Ghosh, Singh, Brij B., Sharma, Kumar, Kasinath, Balakuntalam S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8282273/
https://www.ncbi.nlm.nih.gov/pubmed/34118180
http://dx.doi.org/10.1111/acel.13407