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C/EBP homologous protein deficiency enhances hematopoietic stem cell function via reducing ATF3/ROS‐induced cell apoptosis

Hematopoietic stem cells (HSCs) reside in a quiescent niche to reserve their capacity of self‐renewal. Upon hematopoietic injuries, HSCs enter the cell cycle and encounter protein homeostasis problems caused by accumulation of misfolded proteins. However, the mechanism by which protein homeostasis i...

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Detalles Bibliográficos
Autores principales: Shi, Zhencan, Diao, Daojun, Zhao, Yanan, Luo, Ying, Li, Yafei, Liu, Dingdong, Zhang, Kai, Qiu, Yugang, Yu, Li, Song, Zhangfa, Ju, Zhenyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8282275/
https://www.ncbi.nlm.nih.gov/pubmed/34128315
http://dx.doi.org/10.1111/acel.13382