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Zinc binding alters the conformational dynamics and drives the transport cycle of the cation diffusion facilitator YiiP
YiiP is a secondary transporter that couples Zn(2+) transport to the proton motive force. Structural studies of YiiP from prokaryotes and Znt8 from humans have revealed three different Zn(2+) sites and a conserved homodimeric architecture. These structures define the inward-facing and outward-facing...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Rockefeller University Press
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8282283/ https://www.ncbi.nlm.nih.gov/pubmed/34254979 http://dx.doi.org/10.1085/jgp.202112873 |