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Mendelian randomization analysis provides causality of smoking on the expression of ACE2, a putative SARS-CoV-2 receptor

BACKGROUND: To understand a causal role of modifiable lifestyle factors in angiotensin-converting enzyme 2 (ACE2) expression (a putative severe acute respiratory syndrome coronavirus 2 [SARS-CoV-2] receptor) across 44 human tissues/organs, and in coronavirus disease 2019 (COVID-19) susceptibility an...

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Detalles Bibliográficos
Autores principales: Liu, Hui, Xin, Junyi, Cai, Sheng, Jiang, Xia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8282334/
https://www.ncbi.nlm.nih.gov/pubmed/34227468
http://dx.doi.org/10.7554/eLife.64188