Pharmacokinetics and Tissue Distribution of Combined Triptolide and Paeoniflorin Regimen for Percutaneous Administration in Rats Assessed by Liquid Chromatography-Tandem Mass Spectrometry

Triptolide (TP) has shown potential in rheumatoid arthritis (RA) treatment, but the narrow therapeutic window limits its clinical application. In clinical practice, the compatibility of Tripterygium wilfordii and Paeonia lactiflora is often used to attenuate the toxicity of TP, but its compatibility...

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Detalles Bibliográficos
Autores principales: Guan, Yong-mei, Shen, Qian, He, Liang-fei, Chen, Li-mei, Zang, Zhenzhong, Liu, Lili, Zhu, Wei-feng, Li-hua, Chen, Liu, Hong-ning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8282371/
https://www.ncbi.nlm.nih.gov/pubmed/34306159
http://dx.doi.org/10.1155/2021/8864273

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8282371/
https://www.ncbi.nlm.nih.gov/pubmed/34306159
http://dx.doi.org/10.1155/2021/8864273

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