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Reprogramming astrocytes to motor neurons by activation of endogenous Ngn2 and Isl1

Central nervous system injury and neurodegenerative diseases cause irreversible loss of neurons. Overexpression of exogenous specific transcription factors can reprogram somatic cells into functional neurons for regeneration and functional reconstruction. However, these practices are potentially pro...

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Detalles Bibliográficos
Autores principales: Zhou, Meiling, Tao, Xiaoqing, Sui, Ming, Cui, Mengge, Liu, Dan, Wang, Beibei, Wang, Ting, Zheng, Yunjie, Luo, Juan, Mu, Yangling, Wan, Feng, Zhu, Ling-Qiang, Zhang, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8282467/
https://www.ncbi.nlm.nih.gov/pubmed/34171285
http://dx.doi.org/10.1016/j.stemcr.2021.05.020