Auxin-degron system identifies immediate mechanisms of OCT4

The pluripotency factor OCT4 is essential for the maintenance of naive pluripotent stem cells in vitro and in vivo. However, the specific role of OCT4 in this process remains unknown. Here, we developed a rapid protein-level OCT4 depletion system that demonstrates that the immediate downstream respo...

Descripción completa

Detalles Bibliográficos
Autores principales: Bates, Lawrence E., Alves, Mariana R.P., Silva, José C.R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8282470/
https://www.ncbi.nlm.nih.gov/pubmed/34143975
http://dx.doi.org/10.1016/j.stemcr.2021.05.016

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8282470/
https://www.ncbi.nlm.nih.gov/pubmed/34143975
http://dx.doi.org/10.1016/j.stemcr.2021.05.016

Ejemplares similares