Targeting HIF-1 alpha transcriptional activity drives cytotoxic immune effector cells into melanoma and improves combination immunotherapy

Hypoxia is a key factor responsible for the failure of therapeutic response in most solid tumors and promotes the acquisition of tumor resistance to various antitumor immune effectors. Reshaping the hypoxic immune suppressive tumor microenvironment to improve cancer immunotherapy is still a relevant...

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Detalles Bibliográficos
Autores principales: Lequeux, Audrey, Noman, Muhammad Zaeem, Xiao, Malina, Van Moer, Kris, Hasmim, Meriem, Benoit, Alice, Bosseler, Manon, Viry, Elodie, Arakelian, Tsolere, Berchem, Guy, Chouaib, Salem, Janji, Bassam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8282500/
https://www.ncbi.nlm.nih.gov/pubmed/34155342
http://dx.doi.org/10.1038/s41388-021-01846-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8282500/
https://www.ncbi.nlm.nih.gov/pubmed/34155342
http://dx.doi.org/10.1038/s41388-021-01846-x

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