Systems biology informed neural networks (SBINN) predict response and novel combinations for PD-1 checkpoint blockade

Anti-PD-1 immunotherapy has recently shown tremendous success for the treatment of several aggressive cancers. However, variability and unpredictability in treatment outcome have been observed, and are thought to be driven by patient-specific biology and interactions of the patient’s immune system w...

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Detalles Bibliográficos
Autores principales: Przedborski, Michelle, Smalley, Munisha, Thiyagarajan, Saravanan, Goldman, Aaron, Kohandel, Mohammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8282606/
https://www.ncbi.nlm.nih.gov/pubmed/34267327
http://dx.doi.org/10.1038/s42003-021-02393-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8282606/
https://www.ncbi.nlm.nih.gov/pubmed/34267327
http://dx.doi.org/10.1038/s42003-021-02393-7

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