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Systems biology informed neural networks (SBINN) predict response and novel combinations for PD-1 checkpoint blockade
Anti-PD-1 immunotherapy has recently shown tremendous success for the treatment of several aggressive cancers. However, variability and unpredictability in treatment outcome have been observed, and are thought to be driven by patient-specific biology and interactions of the patient’s immune system w...
Autores principales: | Przedborski, Michelle, Smalley, Munisha, Thiyagarajan, Saravanan, Goldman, Aaron, Kohandel, Mohammad |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8282606/ https://www.ncbi.nlm.nih.gov/pubmed/34267327 http://dx.doi.org/10.1038/s42003-021-02393-7 |
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