Cargando…

Redefining the specificity of phosphoinositide-binding by human PH domain-containing proteins

Pleckstrin homology (PH) domains are presumed to bind phosphoinositides (PIPs), but specific interaction with and regulation by PIPs for most PH domain-containing proteins are unclear. Here we employ a single-molecule pulldown assay to study interactions of lipid vesicles with full-length proteins i...

Descripción completa

Detalles Bibliográficos
Autores principales:	Singh, Nilmani, Reyes-Ordoñez, Adriana, Compagnone, Michael A., Moreno, Jesus F., Leslie, Benjamin J., Ha, Taekjip, Chen, Jie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8282632/ https://www.ncbi.nlm.nih.gov/pubmed/34267198 http://dx.doi.org/10.1038/s41467-021-24639-y

Ejemplares similares

Multiple lipid binding sites determine the affinity of PH domains for phosphoinositide-containing membranes
por: Yamamoto, Eiji, et al.
Publicado: (2020)

Inositol pentakisphosphate isomers bind PH domains with varying specificity and inhibit phosphoinositide interactions
por: Jackson, Sean G, et al.
Publicado: (2011)

Redefining the DNA-Binding Domain of Human XPA
por: Sugitani, Norie, et al.
Publicado: (2014)

Structural Insights Uncover the Specific Phosphoinositide Recognition by the PH1 Domain of Arap3
por: Zhang, Youjia, et al.
Publicado: (2023)

A Conserved Motif in the ITK PH-Domain Is Required for Phosphoinositide Binding and TCR Signaling but Dispensable for Adaptor Protein Interactions
por: Hirve, Nupura, et al.
Publicado: (2012)

Classification of the human phox homology (PX) domains based on their phosphoinositide binding specificities
por: Chandra, Mintu, et al.
Publicado: (2019)

TbFRP, a novel FYVE-domain containing phosphoinositide-binding Ras-like GTPase from trypanosomes
por: Adung’a, Vincent O., et al.
Publicado: (2013)

In Silico Identification and Analysis of Proteins Containing the Phox Homology Phosphoinositide-Binding Domain in Kinetoplastea Protists: Evolutionary Conservation and Uniqueness of Phox-Homology-Domain-Containing Protein Architectures
por: Petsana, Marina, et al.
Publicado: (2023)

Cxcl14 depletion accelerates skeletal myogenesis by promoting cell cycle withdrawal
por: Waldemer-Streyer, Rachel J, et al.
Publicado: (2017)

IQGAP Proteins Reveal an Atypical Phosphoinositide (aPI) Binding Domain with a Pseudo C2 Domain Fold
por: Dixon, Miles J., et al.
Publicado: (2012)

The RNA-Binding Site of Poliovirus 3C Protein Doubles as a Phosphoinositide-Binding Domain
por: Shengjuler, Djoshkun, et al.
Publicado: (2017)

ARHGEF3 Regulates Skeletal Muscle Regeneration and Strength through Autophagy
por: You, Jae-Sung, et al.
Publicado: (2021)

Computational Analysis of the Binding Specificities of PH Domains
por: Jiang, Zhi, et al.
Publicado: (2015)

Cofilin is a pH sensor for actin free barbed end formation: role of phosphoinositide binding
por: Frantz, Christian, et al.
Publicado: (2008)

Visualization of Phosphoinositides That Bind Pleckstrin Homology Domains: Calcium- and Agonist-induced Dynamic Changes and Relationship to Myo-[(3)H]inositol-labeled Phosphoinositide Pools
por: Várnai, Péter, et al.
Publicado: (1998)

SopF, a phosphoinositide binding effector, promotes the stability of the nascent Salmonella-containing vacuole
por: Lau, Nicole, et al.
Publicado: (2019)

Characterisation of a cyclic peptide that binds to the RAS binding domain of phosphoinositide 3-kinase p110α
por: Ismail, Mohamed, et al.
Publicado: (2023)

Increased intracellular Ca(2+) concentrations prevent membrane localization of PH domains through the formation of Ca(2+)-phosphoinositides
por: Kang, Jin Ku, et al.
Publicado: (2017)

Phafins Are More Than Phosphoinositide-Binding Proteins
por: Tang, Tuoxian, et al.
Publicado: (2023)

SH3YL1 regulates dorsal ruffle formation by a novel phosphoinositide-binding domain
por: Hasegawa, Junya, et al.
Publicado: (2011)

Synemin Redefined: Multiple Binding Partners Results in Multifunctionality
por: Russell, Mary A.
Publicado: (2020)

The C2 domain of the Rsp5 ubiquitin ligase binds membrane phosphoinositides and directs ubiquitination of endosomal cargo
por: Dunn, Rebecca, et al.
Publicado: (2004)

YPIBP: A repository for phosphoinositide-binding proteins in yeast
por: Rathod, Jagat, et al.
Publicado: (2021)

Phosphoinositide-binding activity of Smad2 is essential for its function in TGF-β signaling
por: Buwaneka, Pawanthi, et al.
Publicado: (2021)

Redefining the BH3 Death Domain as a ‘Short Linear Motif’
por: Aouacheria, Abdel, et al.
Publicado: (2015)

Alternaria redefined
por: Woudenberg, J.H.C., et al.
Publicado: (2013)

Health: redefined
por: Oleribe, Obinna Ositadimma, et al.
Publicado: (2018)

Redefining ARDS: a paradigm shift
por: Villar, Jesús, et al.
Publicado: (2023)

Dysregulation of Phosphoinositide 5-Phosphatases and Phosphoinositides in Alzheimer's Disease
por: Ando, Kunie, et al.
Publicado: (2021)

Phosphoinositide binding and phosphorylation act sequentially in the activation mechanism of ezrin
por: Fievet, Bruno T., et al.
Publicado: (2004)

Phosphoinositide-binding interface proteins involved in shaping cell membranes
por: TAKENAWA, Tadaomi
Publicado: (2010)

Human V-ATPase a-subunit isoforms bind specifically to distinct phosphoinositide phospholipids
por: Mitra, Connie, et al.
Publicado: (2023)

Kinetic analysis of receptor-activated phosphoinositide turnover
por: Xu, Chang, et al.
Publicado: (2003)

Redefining the architecture of ferlin proteins: Insights into multi-domain protein structure and function
por: Dominguez, Matthew J., et al.
Publicado: (2022)

The acyltransferase LYCAT controls specific phosphoinositides and related membrane traffic
por: Bone, Leslie N., et al.
Publicado: (2017)

Phosphoinositides and phagocytosis
por: Gillooly, David J., et al.
Publicado: (2001)

Redefining territories : the functional regions /
Publicado: (2002)

Dynamic Growth and Shrinkage Govern the pH Dependence of RecA Filament Stability
por: Kim, Sung Hyun, et al.
Publicado: (2015)

Smart grid redefined
por: Vadari, Subramanian
Publicado: (2018)

Redefining the place to learn.
Publicado: (1995)

Cannot write session to /tmp/vufind_sessions/sess_1grg1kfv9199ogp894f2noqiag