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Ist2 recruits the lipid transporters Osh6/7 to ER–PM contacts to maintain phospholipid metabolism

ER-plasma membrane (PM) contacts are proposed to be held together by distinct families of tethering proteins, which in yeast include the VAP homologues Scs2/22, the extended-synaptotagmin homologues Tcb1/2/3, and the TMEM16 homologue Ist2. It is unclear whether these tethers act redundantly or wheth...

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Detalles Bibliográficos
Autores principales: Wong, Andrew King On, Young, Barry Paul, Loewen, Christopher J.R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8282664/
https://www.ncbi.nlm.nih.gov/pubmed/34259806
http://dx.doi.org/10.1083/jcb.201910161