Depdc5 deficiency exacerbates alcohol-induced hepatic steatosis via suppression of PPARα pathway

Alcohol-related liver disease (ALD), a condition caused by alcohol overconsumption, occurs in three stages of liver injury including steatosis, hepatitis, and cirrhosis. DEP domain-containing protein 5 (DEPDC5), a component of GAP activities towards Rags 1 (GATOR1) complex, is a repressor of amino a...

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Detalles Bibliográficos
Autores principales: Xu, Lin, Zhang, Xinge, Xin, Yue, Ma, Jie, Yang, Chenyan, Zhang, Xi, Hou, Guoqing, Dong, Xiaocheng Charlie, Sun, Zhaoli, Xiong, Xiwen, Cao, Xuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8282792/
https://www.ncbi.nlm.nih.gov/pubmed/34267188
http://dx.doi.org/10.1038/s41419-021-03980-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8282792/
https://www.ncbi.nlm.nih.gov/pubmed/34267188
http://dx.doi.org/10.1038/s41419-021-03980-6

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