Quantitative characterization of recombinase-based digitizer circuits enables predictable amplification of biological signals

Many synthetic gene circuits are restricted to single-use applications or require iterative refinement for incorporation into complex systems. One example is the recombinase-based digitizer circuit, which has been used to improve weak or leaky biological signals. Here we present a workflow to quanti...

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Detalles Bibliográficos
Autores principales: Kiwimagi, Katherine A., Letendre, Justin H., Weinberg, Benjamin H., Wang, Junmin, Chen, Mingzhe, Watanabe, Leandro, Myers, Chris J., Beal, Jacob, Wong, Wilson W., Weiss, Ron
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8282836/
https://www.ncbi.nlm.nih.gov/pubmed/34267310
http://dx.doi.org/10.1038/s42003-021-02325-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8282836/
https://www.ncbi.nlm.nih.gov/pubmed/34267310
http://dx.doi.org/10.1038/s42003-021-02325-5

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