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Quantitative characterization of recombinase-based digitizer circuits enables predictable amplification of biological signals
Many synthetic gene circuits are restricted to single-use applications or require iterative refinement for incorporation into complex systems. One example is the recombinase-based digitizer circuit, which has been used to improve weak or leaky biological signals. Here we present a workflow to quanti...
Autores principales: | Kiwimagi, Katherine A., Letendre, Justin H., Weinberg, Benjamin H., Wang, Junmin, Chen, Mingzhe, Watanabe, Leandro, Myers, Chris J., Beal, Jacob, Wong, Wilson W., Weiss, Ron |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8282836/ https://www.ncbi.nlm.nih.gov/pubmed/34267310 http://dx.doi.org/10.1038/s42003-021-02325-5 |
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