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Lack of intrafollicular memory CD4 + T cells is predictive of early clinical failure in newly diagnosed follicular lymphoma

Despite a characteristic indolent course, a substantial subset of follicular lymphoma (FL) patients has an early relapse with a poor outcome. Cells in the microenvironment may be a key contributor to treatment failure. We used a discovery and validation study design to identify microenvironmental de...

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Detalles Bibliográficos
Autores principales: Mondello, Patrizia, Fama, Angelo, Larson, Melissa C., Feldman, Andrew L., Villasboas, Jose C., Yang, Zhi-Zhang, Galkin, Ilia, Svelolkin, Viktor, Postovalova, Ekaterina, Bagaev, Alexander, Ovcharov, Pavel, Varlamova, Arina, Huet, Sarah, Tesson, Bruno, McGrath, Kaitlyn R., Slager, Susan, Link, Brian K., Syrbu, Sergei, Novak, Anne J., Habermann, Thomas M., Witzig, Thomas E., Nowakowski, Grzegorz S., Salles, Gilles, Cerhan, James R., Ansell, Stephen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8282842/
https://www.ncbi.nlm.nih.gov/pubmed/34267181
http://dx.doi.org/10.1038/s41408-021-00521-4