QSAR, molecular docking and ADMET properties in silico studies of novel 4,5,6,7-tetrahydrobenzo[D]-thiazol-2-Yl derivatives derived from dimedone as potent anti-tumor agents through inhibition of C-Met receptor tyrosine kinase

A quantitative structure-activity relationship (QSAR) study is performed on 48 novel 4,5,6,7-tetrahydrobenzo[D]-thiazol-2 derivatives as anticancer agents capable of inhibiting c-Met receptor tyrosine kinase. The present study is conducted using multiple linear regression, multiple nonlinear regress...

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Detalles Bibliográficos
Autores principales: Daoui, Ossama, Elkhattabi, Souad, Chtita, Samir, Elkhalabi, Rachida, Zgou, Hsaine, Benjelloun, Adil Touimi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8282965/
https://www.ncbi.nlm.nih.gov/pubmed/34296007
http://dx.doi.org/10.1016/j.heliyon.2021.e07463

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8282965/
https://www.ncbi.nlm.nih.gov/pubmed/34296007
http://dx.doi.org/10.1016/j.heliyon.2021.e07463

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