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Targeted genomic profiling revealed a unique clinical phenotype in intrahepatic cholangiocarcinoma with fibroblast growth factor receptor rearrangement

Genomic aberrations (GAs) in fibroblast growth factor receptors (FGFRs) are involved in the pathogenesis of intrahepatic cholangiocarcinoma (ICC), and clinical trials have shown efficacy of FGFR inhibitors in treating ICC patients with FGFR GAs such as FGFR2 rearrangement. To clarify the FGFRs GA pr...

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Detalles Bibliográficos
Autores principales: Zhu, Zhongzheng, Dong, Hui, Wu, Jianguo, Dong, Wei, Guo, Xianling, Yu, Hua, Fang, Juemin, Gao, Song, Chen, Xuejun, Lu, Huangbin, Cong, Wenming, Xu, Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8283138/
https://www.ncbi.nlm.nih.gov/pubmed/34252743
http://dx.doi.org/10.1016/j.tranon.2021.101168