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AMPK activation reverts mouse epiblast stem cells to naive state

Despite increasing knowledge on primed and naive pluripotency, the cell signaling that regulates the pluripotency type in stem cells remains not fully understood. Here we show that AMP kinase (AMPK) activators can induce the reversion of primed mouse epiblast stem cells (mEpiSCs) to the naive plurip...

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Detalles Bibliográficos
Autores principales: Liu, Yajing, Yamane, Junko, Tanaka, Akito, Fujibuchi, Wataru, Yamashita, Jun K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8283141/
https://www.ncbi.nlm.nih.gov/pubmed/34308289
http://dx.doi.org/10.1016/j.isci.2021.102783