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FACS-based isolation of fixed mouse neuronal nuclei for ATAC-seq and Hi-C
The organization of chromatin structure plays a crucial role in gene expression, DNA replication, and repair. Chromatin alterations influence gene expression, and modifications could be associated with genomic instability in the cells during aging or diseases. Here, we provide a modified protocol to...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8283150/ https://www.ncbi.nlm.nih.gov/pubmed/34308377 http://dx.doi.org/10.1016/j.xpro.2021.100643 |