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Cell type-specific and cross-population polygenic risk score analyses of MIR137 gene pathway in schizophrenia

Cell type-specific pathway-based polygenic risk scores (PRSs) may better inform disease biology and improve the precision of PRS-based clinical prediction. For microRNA-137 (MIR137), a leading neuropsychiatric risk gene and a post-transcriptional master regulator, we conducted a cell type-specific g...

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Detalles Bibliográficos
Autores principales: Yao, Yin, Guo, Wei, Zhang, Siwei, Yu, Hao, Yan, Hao, Zhang, Hanwen, Sanders, Alan R., Yue, Weihua, Duan, Jubao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8283158/
https://www.ncbi.nlm.nih.gov/pubmed/34308291
http://dx.doi.org/10.1016/j.isci.2021.102785