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Cell type-specific and cross-population polygenic risk score analyses of MIR137 gene pathway in schizophrenia
Cell type-specific pathway-based polygenic risk scores (PRSs) may better inform disease biology and improve the precision of PRS-based clinical prediction. For microRNA-137 (MIR137), a leading neuropsychiatric risk gene and a post-transcriptional master regulator, we conducted a cell type-specific g...
Autores principales: | Yao, Yin, Guo, Wei, Zhang, Siwei, Yu, Hao, Yan, Hao, Zhang, Hanwen, Sanders, Alan R., Yue, Weihua, Duan, Jubao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8283158/ https://www.ncbi.nlm.nih.gov/pubmed/34308291 http://dx.doi.org/10.1016/j.isci.2021.102785 |
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