Loss‐of‐function variants in K(v)11.1 cardiac channels as a biomarker for SUDEP

OBJECTIVE: To compare the frequency and impact on the channel function of KCNH2 variants in SUDEP patients with epilepsy controls comprising patients older than 50 years, a group with low SUDEP risk, and establish loss‐of‐function KCNH2 variants as predictive biomarkers of SUDEP risk. METHODS: We se...

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Detalles Bibliográficos
Autores principales: Soh, Ming S., Bagnall, Richard D., Bennett, Mark F., Bleakley, Lauren E., Mohamed Syazwan, Erlina S., Phillips, A. Marie, Chiam, Mathew D. F., McKenzie, Chaseley E., Hildebrand, Michael, Crompton, Douglas, Bahlo, Melanie, Semsarian, Christopher, Scheffer, Ingrid E., Berkovic, Samuel F., Reid, Christopher A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8283159/
https://www.ncbi.nlm.nih.gov/pubmed/34002542
http://dx.doi.org/10.1002/acn3.51381

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8283159/
https://www.ncbi.nlm.nih.gov/pubmed/34002542
http://dx.doi.org/10.1002/acn3.51381

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