Size-Controlled and Shelf-Stable DNA Particles for Production of Lentiviral Vectors

[Image: see text] Polyelectrolyte complex particles assembled from plasmid DNA (pDNA) and poly(ethylenimine) (PEI) have been widely used to produce lentiviral vectors (LVVs) for gene therapy. The current batch-mode preparation for pDNA/PEI particles presents limited reproducibility in large-scale LV...

Descripción completa

Detalles Bibliográficos
Autores principales: Hu, Yizong, Zhu, Yining, Sutherland, Nolan D., Wilson, David R., Pang, Marion, Liu, Ester, Staub, Jacob R., Berlinicke, Cynthia A., Zack, Donald J., Green, Jordan J., Reddy, Sashank K., Mao, Hai-Quan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8283758/
https://www.ncbi.nlm.nih.gov/pubmed/34228937
http://dx.doi.org/10.1021/acs.nanolett.1c01421

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8283758/
https://www.ncbi.nlm.nih.gov/pubmed/34228937
http://dx.doi.org/10.1021/acs.nanolett.1c01421

Ejemplares similares