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Size-Controlled and Shelf-Stable DNA Particles for Production of Lentiviral Vectors

[Image: see text] Polyelectrolyte complex particles assembled from plasmid DNA (pDNA) and poly(ethylenimine) (PEI) have been widely used to produce lentiviral vectors (LVVs) for gene therapy. The current batch-mode preparation for pDNA/PEI particles presents limited reproducibility in large-scale LV...

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Detalles Bibliográficos
Autores principales:	Hu, Yizong, Zhu, Yining, Sutherland, Nolan D., Wilson, David R., Pang, Marion, Liu, Ester, Staub, Jacob R., Berlinicke, Cynthia A., Zack, Donald J., Green, Jordan J., Reddy, Sashank K., Mao, Hai-Quan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2021
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8283758/ https://www.ncbi.nlm.nih.gov/pubmed/34228937 http://dx.doi.org/10.1021/acs.nanolett.1c01421

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