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Mesenchymal stem cells ameliorate renal fibrosis by galectin-3/Akt/GSK3β/Snail signaling pathway in adenine-induced nephropathy rat

BACKGROUND: Tubulointerstitial fibrosis (TIF) is one of the main pathological features of various progressive renal damages and chronic kidney diseases. Mesenchymal stromal cells (MSCs) have been verified with significant improvement in the therapy of fibrosis diseases, but the mechanism is still un...

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Detalles Bibliográficos
Autores principales: Tang, Huajun, Zhang, Peiyue, Zeng, Lianlin, Zhao, Yu, Xie, Libo, Chen, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8283866/
https://www.ncbi.nlm.nih.gov/pubmed/34271976
http://dx.doi.org/10.1186/s13287-021-02429-z