Effects of a low-dose IL-2 treatment in HLA-B27 transgenic rat model of spondyloarthritis

ABSTRACT: INTRODUCTION/AIM: HLA-B27/human β2m transgenic rats (B27-rats) develop an inflammatory disorder resembling spondyloarthritis (SpA) with dysregulated IL-10/IL-17 production by regulatory T cells (Treg). Treg plays a major role in controlling pathogenic inflammatory processes. Interleukin 2...

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Detalles Bibliográficos
Autores principales: Araujo, L. M., Jouhault, Q., Fert, I., Bouiller, I., Chiocchia, G., Breban, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8283890/
https://www.ncbi.nlm.nih.gov/pubmed/34271972
http://dx.doi.org/10.1186/s13075-021-02559-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8283890/
https://www.ncbi.nlm.nih.gov/pubmed/34271972
http://dx.doi.org/10.1186/s13075-021-02559-y

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