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Remdesivir Inhibits Tubulointerstitial Fibrosis in Obstructed Kidneys

Aim: Kidney impairment is observed in patients with COVID-19. The effect of anti-COVID-19 agent remdesivir on kidneys is currently unknown. We aimed to determine the effect of remdesivir on renal fibrosis and its downstream mechanisms. Methods: Remdesivir and its active nucleoside metabolite GS-4415...

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Detalles Bibliográficos
Autores principales: Xu, Lin, Tan, Bo, Huang, Di, Yuan, Meijie, Li, Tingting, Wu, Ming, Ye, Chaoyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8284048/
https://www.ncbi.nlm.nih.gov/pubmed/34276356
http://dx.doi.org/10.3389/fphar.2021.626510