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Production of full-length SARS-CoV-2 nucleocapsid protein from Escherichia coli optimized by native hydrophobic interaction chromatography hyphenated to multi-angle light scattering detection

The nucleocapsid protein (NP) of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is critical for several steps of the viral life cycle, and is abundantly expressed during infection, making it an ideal diagnostic target protein. This protein has a strong tendency for dimerization and int...

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Detalles Bibliográficos
Autores principales: De Vos, Jelle, Pereira Aguilar, Patricia, Köppl, Christoph, Fischer, Andreas, Grünwald-Gruber, Clemens, Dürkop, Mark, Klausberger, Miriam, Mairhofer, Juergen, Striedner, Gerald, Cserjan-Puschmann, Monika, Jungbauer, Alois, Lingg, Nico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Published by Elsevier B.V. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8284068/
https://www.ncbi.nlm.nih.gov/pubmed/34517577
http://dx.doi.org/10.1016/j.talanta.2021.122691