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Females, but not males, require protein degradation in the hippocampus for contextual fear memory formation
Strong evidence supports a role for protein degradation in fear memory formation. However, these data have been largely done in only male animals. Here, we found that following contextual fear conditioning, females, but not males, had increased levels of proteasome activity and K48 polyubiquitin pro...
Autores principales: | Martin, Kiley, Musaus, Madeline, Navabpour, Shaghayegh, Gustin, Aspen, Ray, W. Keith, Helm, Richard F., Jarome, Timothy J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8284313/ https://www.ncbi.nlm.nih.gov/pubmed/34266989 http://dx.doi.org/10.1101/lm.053429.121 |
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