Structure and mechanism of Mycobacterium smegmatis polynucleotide phosphorylase

Polynucleotide phosphorylase (PNPase) catalyzes stepwise phosphorolysis of the 3′-terminal phosphodiesters of RNA chains to yield nucleoside diphosphate products. In the reverse reaction, PNPase acts as a polymerase, using NDPs as substrates to add NMPs to the 3′-OH terminus of RNA chains while expe...

Descripción completa

Detalles Bibliográficos
Autores principales: Unciuleac, Mihaela-Carmen, Ghosh, Shreya, de la Cruz, M. Jason, Goldgur, Yehuda, Shuman, Stewart
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8284320/
https://www.ncbi.nlm.nih.gov/pubmed/34088850
http://dx.doi.org/10.1261/rna.078822.121

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8284320/
https://www.ncbi.nlm.nih.gov/pubmed/34088850
http://dx.doi.org/10.1261/rna.078822.121

Ejemplares similares