Fusion protein EWS-FLI1 is incorporated into a protein granule in cells

Ewing sarcoma is driven by fusion proteins containing a low-complexity (LC) domain that is intrinsically disordered and a powerful transcriptional regulator. The most common fusion protein found in Ewing sarcoma, EWS-FLI1, takes its LC domain from the RNA-binding protein EWSR1 (Ewing sarcoma RNA-bin...

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Detalles Bibliográficos
Autores principales: Ahmed, Nasiha S., Harrell, Lucas M., Wieland, Daniel R., Lay, Michelle A., Thompson, Valery F., Schwartz, Jacob C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8284321/
https://www.ncbi.nlm.nih.gov/pubmed/34035145
http://dx.doi.org/10.1261/rna.078827.121

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8284321/
https://www.ncbi.nlm.nih.gov/pubmed/34035145
http://dx.doi.org/10.1261/rna.078827.121

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