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IsoSplitter: identification and characterization of alternative splicing sites without a reference genome

Long-read transcriptome sequencing is designed to sequence full-length RNA molecules and advantageous for identifying alternative splice isoforms; however, in the absence of a reference genome, it is difficult to accurately locate splice sites because of the diversity of patterns of alternative spli...

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Detalles Bibliográficos
Autores principales: Wang, Yupeng, Hu, Zhikang, Ye, Ning, Yin, Hengfu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8284324/
https://www.ncbi.nlm.nih.gov/pubmed/34021065
http://dx.doi.org/10.1261/rna.077834.120