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In Vitro Profiling of Antitubercular Compounds by Rapid, Efficient, and Nondestructive Assays Using Autoluminescent Mycobacterium tuberculosis

Anti-infective drug discovery is greatly facilitated by the availability of in vitro assays that are more proficient at predicting the preclinical success of screening hits. Tuberculosis (TB) drug discovery is hindered by the relatively slow growth rate of Mycobacterium tuberculosis and the use of w...

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Detalles Bibliográficos
Autores principales: Shetye, Gauri S., Choi, Kyung Bae, Kim, Chang-Yub, Franzblau, Scott G., Cho, Sanghyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8284454/
https://www.ncbi.nlm.nih.gov/pubmed/34097493
http://dx.doi.org/10.1128/AAC.00282-21