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Megakaryocyte production is sustained by direct differentiation from erythromyeloid progenitors in the yolk sac until midgestation

The extra-embryonic yolk sac contains the first definitive multipotent hematopoietic cells, denominated erythromyeloid progenitors. They originate in situ prior to the emergence of hematopoietic stem cells and give rise to erythroid, monocytes, granulocytes, mast cells and macrophages, the latter in...

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Detalles Bibliográficos
Autores principales: Iturri, Lorea, Freyer, Laina, Biton, Anne, Dardenne, Pascal, Lallemand, Yvan, Gomez Perdiguero, Elisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8284597/
https://www.ncbi.nlm.nih.gov/pubmed/34062116
http://dx.doi.org/10.1016/j.immuni.2021.04.026