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Genetic engineering of Treponema pallidum subsp. pallidum, the Syphilis Spirochete

Despite more than a century of research, genetic manipulation of Treponema pallidum subsp. pallidum (T. pallidum), the causative agent of syphilis, has not been successful. The lack of genetic engineering tools has severely limited understanding of the mechanisms behind T. pallidum success as a path...

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Detalles Bibliográficos
Autores principales: Romeis, Emily, Tantalo, Lauren, Lieberman, Nicole, Phung, Quynh, Greninger, Alex, Giacani, Lorenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8284648/
https://www.ncbi.nlm.nih.gov/pubmed/34228757
http://dx.doi.org/10.1371/journal.ppat.1009612