Interleukin-15 response signature predicts RhCMV/SIV vaccine efficacy

Simian immunodeficiency virus (SIV) challenge of rhesus macaques (RMs) vaccinated with strain 68–1 Rhesus Cytomegalovirus (RhCMV) vectors expressing SIV proteins (RhCMV/SIV) results in a binary outcome: stringent control and subsequent clearance of highly pathogenic SIV in ~55% of vaccinated RMs wit...

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Detalles Bibliográficos
Autores principales: Barrenäs, Fredrik, Hansen, Scott G., Law, Lynn, Driscoll, Connor, Green, Richard R., Smith, Elise, Chang, Jean, Golez, Inah, Urion, Taryn, Peng, Xinxia, Whitmore, Leanne, Newhouse, Daniel, Hughes, Colette M., Morrow, David, Randall, Kurt T., Selseth, Andrea N., Ford, Julia C., Gilbride, Roxanne M., Randall, Bryan E., Ainslie, Emily, Oswald, Kelli, Shoemaker, Rebecca, Fast, Randy, Bosche, William J., Axthelm, Michael K., Fukazawa, Yoshinori, Pavlakis, George N., Felber, Barbara K., Fourati, Slim, Sekaly, Rafick-Pierre, Lifson, Jeffrey D., Komorowski, Jan, Kosmider, Ewelina, Shao, Danica, Song, Wenjun, Edlefsen, Paul T., Picker, Louis J., Gale, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8284654/
https://www.ncbi.nlm.nih.gov/pubmed/34228762
http://dx.doi.org/10.1371/journal.ppat.1009278

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8284654/
https://www.ncbi.nlm.nih.gov/pubmed/34228762
http://dx.doi.org/10.1371/journal.ppat.1009278

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