CRISPR/Cas9 modified An. gambiae carrying kdr mutation L1014F functionally validate its contribution in insecticide resistance and combined effect with metabolic enzymes

Insecticide resistance in Anopheles mosquitoes is a major obstacle in maintaining the momentum in reducing the malaria burden; mitigating strategies require improved understanding of the underlying mechanisms. Mutations in the target site of insecticides (the voltage gated sodium channel for the mos...

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Detalles Bibliográficos
Autores principales: Grigoraki, Linda, Cowlishaw, Ruth, Nolan, Tony, Donnelly, Martin, Lycett, Gareth, Ranson, Hilary
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8284791/
https://www.ncbi.nlm.nih.gov/pubmed/34228718
http://dx.doi.org/10.1371/journal.pgen.1009556

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8284791/
https://www.ncbi.nlm.nih.gov/pubmed/34228718
http://dx.doi.org/10.1371/journal.pgen.1009556

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