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NuA4 and SAGA acetyltransferase complexes cooperate for repair of DNA breaks by homologous recombination

Chromatin modifying complexes play important yet not fully defined roles in DNA repair processes. The essential NuA4 histone acetyltransferase (HAT) complex is recruited to double-strand break (DSB) sites and spreads along with DNA end resection. As predicted, NuA4 acetylates surrounding nucleosomes...

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Detalles Bibliográficos
Autores principales: Cheng, Xue, Côté, Valérie, Côté, Jacques
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8284799/
https://www.ncbi.nlm.nih.gov/pubmed/34228704
http://dx.doi.org/10.1371/journal.pgen.1009459