Prioritizing and characterizing functionally relevant genes across human tissues

Knowledge of genes that are critical to a tissue’s function remains difficult to ascertain and presents a major bottleneck toward a mechanistic understanding of genotype-phenotype links. Here, we present the first machine learning model–FUGUE–combining transcriptional and network features, to predic...

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Detalles Bibliográficos
Autores principales: Somepalli, Gowthami, Sahoo, Sarthak, Singh, Arashdeep, Hannenhalli, Sridhar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8284802/
https://www.ncbi.nlm.nih.gov/pubmed/34270548
http://dx.doi.org/10.1371/journal.pcbi.1009194

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8284802/
https://www.ncbi.nlm.nih.gov/pubmed/34270548
http://dx.doi.org/10.1371/journal.pcbi.1009194

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