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Polycomb-group recruitment to a Drosophila target gene is the default state that is inhibited by a transcriptional activator

Polycomb-group (PcG) proteins are epigenetic regulators that maintain the transcriptional repression of target genes following their initial repression by transcription factors. PcG target genes are repressed in some cells, but active in others. Therefore, a mechanism must exist by which PcG protein...

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Detalles Bibliográficos
Autores principales: Ghotbi, Elnaz, Ye, Piao, Ervin, Taylor, Kum, Anni, Benes, Judith, Jones, Richard S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8284896/
https://www.ncbi.nlm.nih.gov/pubmed/34272248
http://dx.doi.org/10.1126/sciadv.abg1556