7,8-Dihydroxyflavone modulates bone formation and resorption and ameliorates ovariectomy-induced osteoporosis

Imbalances in bone formation and resorption cause osteoporosis. Mounting evidence supports that brain-derived neurotrophic factor (BDNF) implicates in this process. 7,8-Dihydroxyflavone (7,8-DHF), a plant-derived small molecular TrkB agonist, mimics the functions of BDNF. We show that both BDNF and...

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Detalles Bibliográficos
Autores principales: Xue, Fan, Zhao, Zhenlei, Gu, Yanpei, Han, Jianxin, Ye, Keqiang, Zhang, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8285109/
https://www.ncbi.nlm.nih.gov/pubmed/34227467
http://dx.doi.org/10.7554/eLife.64872

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8285109/
https://www.ncbi.nlm.nih.gov/pubmed/34227467
http://dx.doi.org/10.7554/eLife.64872

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