Safety and Immunogenicity of a DNA SARS-CoV-2 vaccine (ZyCoV-D): Results of an open-label, non-randomized phase I part of phase I/II clinical study by intradermal route in healthy subjects in India

BACKGROUND: ZyCoV-D is a DNA vaccine candidate, which comprises a plasmid DNA carrying spike-S gene of SARS-CoV-2 virus along with gene coding for signal peptide. The spike(S) region includes the receptor-binding domain (RBD), which binds to the human angiotensin converting Enzyme (ACE)-2 receptor a...

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Detalles Bibliográficos
Autores principales: Momin, Taufik, Kansagra, Kevinkumar, Patel, Hardik, Sharma, Sunil, Sharma, Bhumika, Patel, Jatin, Mittal, Ravindra, Sanmukhani, Jayesh, Maithal, Kapil, Dey, Ayan, Chandra, Harish, Rajanathan, Chozhavel TM, Pericherla, Hari PR, Kumar, Pawan, Narkhede, Anjali, Parmar, Deven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8285262/
https://www.ncbi.nlm.nih.gov/pubmed/34308319
http://dx.doi.org/10.1016/j.eclinm.2021.101020

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8285262/
https://www.ncbi.nlm.nih.gov/pubmed/34308319
http://dx.doi.org/10.1016/j.eclinm.2021.101020

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