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Alternative Lengthening of Telomeres (ALT) in Pancreatic Neuroendocrine Tumors: Ready for Prime-Time in Clinical Practice?

PURPOSE OF REVIEW: Alternative lengthening of telomeres (ALT) is a telomerase-independent mechanism used by some types of malignancies, including pancreatic neuroendocrine tumors, to overcome the issue of telomere shortening, thus supporting tumor growth and cell proliferation. This review is focuse...

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Detalles Bibliográficos
Autores principales: Luchini, Claudio, Lawlor, Rita T., Bersani, Samantha, Vicentini, Caterina, Paolino, Gaetano, Mattiolo, Paola, Pea, Antonio, Cingarlini, Sara, Milella, Michele, Scarpa, Aldo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8285324/
https://www.ncbi.nlm.nih.gov/pubmed/34269919
http://dx.doi.org/10.1007/s11912-021-01096-w