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Glucose limitation activates AMPK coupled SENP1-Sirt3 signalling in mitochondria for T cell memory development

Metabolic programming and mitochondrial dynamics along with T cell differentiation affect T cell fate and memory development; however, how to control metabolic reprogramming and mitochondrial dynamics in T cell memory development is unclear. Here, we provide evidence that the SUMO protease SENP1 pro...

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Detalles Bibliográficos
Autores principales: He, Jianli, Shangguan, Xun, Zhou, Wei, Cao, Ying, Zheng, Quan, Tu, Jun, Hu, Gaolei, Liang, Zi, Jiang, Cen, Deng, Liufu, Wang, Shengdian, Yang, Wen, Zuo, Yong, Ma, Jiao, Cai, Rong, Chen, Yalan, Fan, Qiuju, Dong, Baijun, Xue, Wei, Tan, Hongsheng, Qi, Yitao, Gu, Jianmin, Su, Bing, Eugene Chin, Y., Chen, Guoqiang, Wang, Qi, Wang, Tianshi, Cheng, Jinke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8285428/
https://www.ncbi.nlm.nih.gov/pubmed/34272364
http://dx.doi.org/10.1038/s41467-021-24619-2