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Organozinc pivalates for cobalt-catalyzed difluoroalkylarylation of alkenes
Installation of fluorine into pharmaceutically relevant molecules plays a vital role in their properties of biology or medicinal chemistry. Direct difunctionalization of alkenes and 1,3-dienes to achieve fluorinated compounds through transition-metal catalysis is challenging, due to the facile β-H e...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8285467/ https://www.ncbi.nlm.nih.gov/pubmed/34272392 http://dx.doi.org/10.1038/s41467-021-24596-6 |