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FOXO3a protects glioma cells against temozolomide-induced DNA double strand breaks via promotion of BNIP3-mediated mitophagy

FOXO3a (forkhead box transcription factor 3a) is involved in regulating multiple biological processes in cancer cells. BNIP3 (Bcl-2/adenovirus E1B 19-kDa-interacting protein 3) is a receptor accounting for priming damaged mitochondria for autophagic removal. In this study we investigated the role of...

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Detalles Bibliográficos
Autores principales: He, Chuan, Lu, Shan, Wang, Xuan-zhong, Wang, Chong-cheng, Wang, Lei, Liang, Shi-peng, Luo, Tian-fei, Wang, Zhen-chuan, Piao, Mei-hua, Chi, Guang-fan, Ge, Peng-fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8285492/
https://www.ncbi.nlm.nih.gov/pubmed/33879840
http://dx.doi.org/10.1038/s41401-021-00663-y