Innate-like self-reactive B cells infiltrate human renal allografts during transplant rejection

Intrarenal B cells in human renal allografts indicate transplant recipients with a poor prognosis, but how these cells contribute to rejection is unclear. Here we show using single-cell RNA sequencing that intrarenal class-switched B cells have an innate cell transcriptional state resembling mouse p...

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Detalles Bibliográficos
Autores principales: Asano, Yuta, Daccache, Joe, Jain, Dharmendra, Ko, Kichul, Kinloch, Andrew, Veselits, Margaret, Wolfgeher, Donald, Chang, Anthony, Josephson, Michelle, Cunningham, Patrick, Tambur, Anat, Khan, Aly A., Pillai, Shiv, Chong, Anita S., Clark, Marcus R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8285506/
https://www.ncbi.nlm.nih.gov/pubmed/34272370
http://dx.doi.org/10.1038/s41467-021-24615-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8285506/
https://www.ncbi.nlm.nih.gov/pubmed/34272370
http://dx.doi.org/10.1038/s41467-021-24615-6

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