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Innate-like self-reactive B cells infiltrate human renal allografts during transplant rejection
Intrarenal B cells in human renal allografts indicate transplant recipients with a poor prognosis, but how these cells contribute to rejection is unclear. Here we show using single-cell RNA sequencing that intrarenal class-switched B cells have an innate cell transcriptional state resembling mouse p...
Autores principales: | Asano, Yuta, Daccache, Joe, Jain, Dharmendra, Ko, Kichul, Kinloch, Andrew, Veselits, Margaret, Wolfgeher, Donald, Chang, Anthony, Josephson, Michelle, Cunningham, Patrick, Tambur, Anat, Khan, Aly A., Pillai, Shiv, Chong, Anita S., Clark, Marcus R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8285506/ https://www.ncbi.nlm.nih.gov/pubmed/34272370 http://dx.doi.org/10.1038/s41467-021-24615-6 |
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