Mechanisms and consequences of casein kinase II and ankyrin-3 regulation of the epithelial Na(+) channel

Activity of the Epithelial Na(+) Channel (ENaC) in the distal nephron fine-tunes renal sodium excretion. Appropriate sodium excretion is a key factor in the regulation of blood pressure. Consequently, abnormalities in ENaC function can cause hypertension. Casein Kinase II (CKII) phosphorylates ENaC....

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Detalles Bibliográficos
Autores principales: Abd El-Aziz, Tarek Mohamed, Soares, Antonio G., Mironova, Elena, Boiko, Nina, Kaur, Amanpreet, Archer, Crystal R., Stockand, James D., Berman, Jonathan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8285517/
https://www.ncbi.nlm.nih.gov/pubmed/34272444
http://dx.doi.org/10.1038/s41598-021-94118-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8285517/
https://www.ncbi.nlm.nih.gov/pubmed/34272444
http://dx.doi.org/10.1038/s41598-021-94118-3

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